Transforming Brain Health

The Mindstrong Health Mission:
Better Outcomes Through Measurement-Based Care

Our Formidable Challenge: Transforming Healthcare
In this decade, neuropsychiatric disorders represent the largest source of medical disability for people under age 50. The costs are among the highest of all medical disorders, in part because mental disorders begin early and can result in many years lost to disability. For people in the second half of life, neurodegenerative disorders are becoming increasingly prevalent, with dementia affecting one in three over age 80. Our best hope for improving outcomes for people with neurodevelopmental and neurodegenerative disorders is early prediction and preemptive interventions.

High costs, poor outcomes, and late detection are driven, in part, by a lack of valid, objective measurement where and when it matters most — in a person’s day-to-day environment. Progress depends on having better data through rigorous, real-world measurement.

How to Transform Healthcare

Clinical Trials

Clinical researchers rely on episodic, subjective assessments of symptoms that do not translate well to day-to-day function. Current assessments not only lack precision for measuring outcomes, they lack precision for diagnosis, resulting in trials that mix people with similar symptoms but potentially different disorders. This “diagnostic heterogeneity” is an inescapable challenge for testing new treatments in neuropsychiatric disorders.

Clinical Practice

Neuropsychiatric care is one of the few areas of medicine that does not measure progress with objective tools. We don’t manage what we don’t measure. Research has shown that mental health clinicians fail to detect worsening in 4 of 5 patients who experience increased symptom severity. National policy experts have declared that measurement-based care is an urgent priority for improving mental health outcomes. (Fortney et al., 2016)

Our Approach


Digital phenotyping is the core of our measurement approach. Digital phenotyping is simply assessment based on smartphone use.  As smartphones have become ubiquitous, their increasing use provides an unprecedented opportunity to measure mood, cognition, and behavior – passively, objectively, and continuously.


Technologies like digital phenotyping offer a revolution in healthcare. As with all technologies, there is a risk that the promise of progress could be tempered by the misuse of a powerful new tool. Smartphone data is also personal data, data that must be protected. Mindstrong Health is committed to ensuring public trust by employing the highest levels of privacy protection, engaging patients and families in research and development, and working with national experts in the ethics of digital healthcare.

Our Goals


Better Outcomes Across Every Population

Our lack of detection leads to egregious delays in treatment. A recent U.S. study reported a duration of untreated psychosis of 74 weeks. (Addington et al, 2015) Poor outcomes can be attributed to the delay in getting care and care that is reactive, not proactive.


Preempting Disease and Intercepting Relapse

It is going to take more than a measurement-based approach to transform healthcare. Measurement is our foundation for a new platform of interventions that will ensure better outcomes, with a goal of intercepting illness at an early stage and enhancing recovery at a later stage.


The Learning Healthcare System

At Mindstrong we believe in data, not only because we need better measures of outcome and more precise diagnoses, but also because we need a healthcare system that learns from each interaction.

About Us

Mindstrong was founded by three of the world’s leading authorities in neuroscience, medicine, and artificial intelligence. It is based on their shared vision to redefine neuropsychiatric healthcare, transforming diagnosis and delivering precision therapy. Mindstrong builds on one of the founder’s patented digital phenotyping platform developed over years of extensive clinical R&D.

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